GENETIC AND PHARMACOLOGICAL INHIBITION OF TTK IMPAIRS PANCREATIC CANCER CELL LINE GROWTH BY INDUCING LETHAL CHROMOSOMAL INSTABILITY.

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.

Pancreatic ductal adenocarcinoma, which accounts for the majority of pancreatic cancers, is a lethal disease with few therapeutic options.Genomic profiling of pancreatic ductal adenocarcinoma has identified a complex Bassinet and heterogeneous landscape.Understanding the molecular characteristics of pancreatic ductal adenocarcinoma will facilitate

read more